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Limited Polymorphism of the Kelch Propeller Domain in Plasmodium malariae and P. ovale Isolates from Thailand

Artemisinin resistance in Plasmodium falciparum, the agent of severe malaria, is currently a major obstacle to malaria control in Southeast Asia. A gene named “kelch13” has been associated with artemisinin resistance in P. falciparum. The orthologue of the kelch gene in P. vivax was identified and a...

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Detalles Bibliográficos
Autores principales: Nakeesathit, Supatchara, Saralamba, Naowarat, Pukrittayakamee, Sasithon, Dondorp, Arjen, Nosten, Francois, White, Nicholas J., Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914644/
https://www.ncbi.nlm.nih.gov/pubmed/27114275
http://dx.doi.org/10.1128/AAC.00138-16