Structural studies of neuropilin‐2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket

Neuropilin‐2 is a transmembrane receptor involved in lymphangiogenesis and neuronal development. In adults, neuropilin‐2 and its homologous protein neuropilin‐1 have been implicated in cancers and infection. Molecular determinants of the ligand selectivity of neuropilins are poorly understood. We ha...

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Detalles Bibliográficos
Autores principales: Tsai, Yi‐Chun Isabella, Fotinou, Constantina, Rana, Rohini, Yelland, Tamas, Frankel, Paul, Zachary, Ian, Djordjevic, Snezana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914954/
https://www.ncbi.nlm.nih.gov/pubmed/26991001
http://dx.doi.org/10.1111/febs.13711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914954/
https://www.ncbi.nlm.nih.gov/pubmed/26991001
http://dx.doi.org/10.1111/febs.13711

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