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Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival

The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell mass. Nutrients such as free fatty acids (FFAs) contrib...

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Detalles Bibliográficos
Autores principales: Villa, Stephanie R., Priyadarshini, Medha, Fuller, Miles H., Bhardwaj, Tanya, Brodsky, Michael R., Angueira, Anthony R., Mosser, Rockann E., Carboneau, Bethany A., Tersey, Sarah A., Mancebo, Helena, Gilchrist, Annette, Mirmira, Raghavendra G., Gannon, Maureen, Layden, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914960/
https://www.ncbi.nlm.nih.gov/pubmed/27324831
http://dx.doi.org/10.1038/srep28159