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Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival
The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell mass. Nutrients such as free fatty acids (FFAs) contrib...
Autores principales: | Villa, Stephanie R., Priyadarshini, Medha, Fuller, Miles H., Bhardwaj, Tanya, Brodsky, Michael R., Angueira, Anthony R., Mosser, Rockann E., Carboneau, Bethany A., Tersey, Sarah A., Mancebo, Helena, Gilchrist, Annette, Mirmira, Raghavendra G., Gannon, Maureen, Layden, Brian T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914960/ https://www.ncbi.nlm.nih.gov/pubmed/27324831 http://dx.doi.org/10.1038/srep28159 |
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