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Non-homologous end joining repair in Xenopus egg extract

Non-homologous end joining (NHEJ) is a major DNA double-strand break (DSB) repair mechanism. We characterized here a series of plasmid-based DSB templates that were repaired in Xenopus egg extracts via the canonical, Ku-dependent NHEJ pathway. We showed that the template with compatible ends was eff...

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Detalles Bibliográficos
Autores principales: Zhu, Songli, Peng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914968/
https://www.ncbi.nlm.nih.gov/pubmed/27324260
http://dx.doi.org/10.1038/srep27797