Protection against doxorubicin-induced myocardial dysfunction in mice by cardiac-specific expression of carboxyl terminus of hsp70-interacting protein

Carboxyl terminus of Hsp70-interacting protein (CHIP) is a critical ubiquitin ligase/cochaperone to reduce cardiac oxidative stress, inflammation, cardiomyocyte apoptosis and autophage etc. However, it is unclear whether overexpression of CHIP in the heart would exert protective effects against DOX-...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lei, Zhang, Tian-Peng, Zhang, Yuan, Bi, Hai-Lian, Guan, Xu-Min, Wang, Hong-Xia, Wang, Xia, Du, Jie, Xia, Yun-Long, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914971/
https://www.ncbi.nlm.nih.gov/pubmed/27323684
http://dx.doi.org/10.1038/srep28399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914971/
https://www.ncbi.nlm.nih.gov/pubmed/27323684
http://dx.doi.org/10.1038/srep28399

Ejemplares similares