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Down-regulation of HSP60 Suppresses the Proliferation of Glioblastoma Cells via the ROS/AMPK/mTOR Pathway

Glioblastoma is a fatal and incurable cancer with the hyper-activated mTOR pathway. HSP60, a major chaperone for maintenance of mitochondrial proteostasis, is highly expressed in glioblastoma patients. To understand the effects of HSP60 on glioblastoma tumorigenesis and progression, we characterized...

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Detalles Bibliográficos
Autores principales:	Tang, Haiping, Li, Jin, Liu, Xiaohui, Wang, Guihuai, Luo, Minkui, Deng, Haiteng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914999/ https://www.ncbi.nlm.nih.gov/pubmed/27325206 http://dx.doi.org/10.1038/srep28388

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