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MtrA of the sodium ion pumping methyltransferase binds cobalamin in a unique mode

In the three domains of life, vitamin B(12) (cobalamin) is primarily used in methyltransferase and isomerase reactions. The methyltransferase complex MtrA–H of methanogenic archaea has a key function in energy conservation by catalysing the methyl transfer from methyl-tetrahydromethanopterin to coen...

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Detalles Bibliográficos
Autores principales: Wagner, Tristan, Ermler, Ulrich, Shima, Seigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915002/
https://www.ncbi.nlm.nih.gov/pubmed/27324530
http://dx.doi.org/10.1038/srep28226