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Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restriction

BACKGROUND: Intrauterine growth restriction (IUGR), which refers to reduced fetal growth in the context of placental insufficiency, is etiologically heterogeneous. IUGR is associated not only with perinatal morbidity and mortality but also with adult-onset disorders, such as cardiovascular disease a...

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Detalles Bibliográficos
Autores principales: Roifman, Maian, Choufani, Sanaa, Turinsky, Andrei L., Drewlo, Sascha, Keating, Sarah, Brudno, Michael, Kingdom, John, Weksberg, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915063/
https://www.ncbi.nlm.nih.gov/pubmed/27330572
http://dx.doi.org/10.1186/s13148-016-0238-x