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The preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8

BACKGROUND: Resiniferatoxin (RTX) is a potent analog of capsaicin and activates transient receptor potential (TRP) vanilloid type (TRPV) 1. In the current study, we investigated the preventive effect of perineural RTX on the development of cold hypersensitivity induced by spinal nerve ligation (SNL)...

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Detalles Bibliográficos
Autores principales: Koh, Won Uk, Choi, Seong-Soo, Kim, Ji Hyun, Yoon, Hye Joo, Ahn, Ho-Soo, Lee, Sun Kyung, Leem, Jeong Gil, Song, Jun Gol, Shin, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915067/
https://www.ncbi.nlm.nih.gov/pubmed/27329106
http://dx.doi.org/10.1186/s12868-016-0273-8