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αT-catenin in restricted brain cell types and its potential connection to autism

BACKGROUND: Recent genetic association studies have linked the cadherin-based adherens junction protein alpha-T-catenin (αT-cat, CTNNA3) with the development of autism. Where αT-cat is expressed in the brain, and how its loss could contribute to this disorder, are entirely unknown. METHODS: We used...

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Detalles Bibliográficos
Autores principales: Folmsbee, Stephen Sai, Wilcox, Douglas R., Tyberghein, Koen, De Bleser, Pieter, Tourtellotte, Warren G., van Hengel, Jolanda, van Roy, Frans, Gottardi, Cara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915096/
https://www.ncbi.nlm.nih.gov/pubmed/27330745
http://dx.doi.org/10.1186/s40303-016-0017-9