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IGF1 potentiates BMP9-induced osteogenic differentiation in mesenchymal stem cells through the enhancement of BMP/Smad signaling

Engineered bone tissue is thought to be the ideal alternative for bone grafts in the treatment of related bone diseases. BMP9 has been demonstrated as one of the most osteogenic factors, and enhancement of BMP9-induced osteogenesis will greatly accelerate the development of bone tissue engineering....

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Detalles Bibliográficos
Autores principales: Chen, Liang, Zou, Xiang, Zhang, Ran-Xi, Pi, Chang-Jun, Wu, Nian, Yin, Liang-Jun, Deng, Zhong-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915116/
https://www.ncbi.nlm.nih.gov/pubmed/26645636
http://dx.doi.org/10.5483/BMBRep.2016.49.2.228