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Donating Otx2 to support neighboring neuron survival

Mutations of orthodentricle homeobox 2 (OTX2) in human and mice often cause retinal dystrophy and nyctalopia, suggesting a role of OTX2 in mature retina, in addition to its functions in the development of the eye and retina. In support of this, the number of bipolar cells in Otx2(+/−) post-natal mou...

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Detalles Bibliográficos
Autores principales: Kim, Hyoung-Tai, Prochiantz, Alain, Kim, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915118/
https://www.ncbi.nlm.nih.gov/pubmed/26779998
http://dx.doi.org/10.5483/BMBRep.2016.49.2.006