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The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster
Insulin/insulin-like growth factor (IGF)-1 signaling (IIS) pathway regulates aging in many organisms, ranging from simple invertebrates to mammals, including humans. Many seminal discoveries regarding the roles of IIS in aging and longevity have been made by using the roundworm Caenorhabditis elegan...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular
Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915121/ https://www.ncbi.nlm.nih.gov/pubmed/26698870 http://dx.doi.org/10.5483/BMBRep.2016.49.2.261 |