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Non-histone protein HMGB1 inhibits the repair of damaged DNA by cisplatin in NIH-3T3 murine fibroblasts

The nuclear non-histone protein high mobility group box (HMGB) 1 is known to having an inhibitory effect on the repair of DNA damaged by the antitumor drug cisplatin in vitro. To investigate the role of HMGB1 in living cells, we studied the DNA repair of cisplatin damages in mouse fibroblast cell li...

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Detalles Bibliográficos
Autores principales: Yusein-Myashkova, Shazie, Ugrinova, Iva, Pasheva, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915123/
https://www.ncbi.nlm.nih.gov/pubmed/24325815
http://dx.doi.org/10.5483/BMBRep.2016.49.2.238