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Structural insights of ZIP4 extracellular domain critical for optimal zinc transport

The ZIP zinc transporter family is responsible for zinc uptake from the extracellular milieu or intracellular vesicles. The LIV-1 subfamily, containing nine out of the 14 human ZIP proteins, is featured with a large extracellular domain (ECD). The critical role of the ECD is manifested by disease-ca...

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Detalles Bibliográficos
Autores principales: Zhang, Tuo, Sui, Dexin, Hu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915132/
https://www.ncbi.nlm.nih.gov/pubmed/27321477
http://dx.doi.org/10.1038/ncomms11979