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Local injection of bone marrow progenitor cells for the treatment of anal sphincter injury: in-vitro expanded versus minimally-manipulated cells

BACKGROUND: Anal incontinence is a disabling condition that adversely affects the quality of life of a large number of patients, mainly with anal sphincter lesions. In a previous experimental work, in-vitro expanded bone marrow (BM)-derived mesenchymal stem cells (MSC) were demonstrated to enhance s...

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Detalles Bibliográficos
Autores principales: Mazzanti, Benedetta, Lorenzi, Bruno, Borghini, Annalisa, Boieri, Margherita, Ballerini, Lara, Saccardi, Riccardo, Weber, Elisabetta, Pessina, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915145/
https://www.ncbi.nlm.nih.gov/pubmed/27328811
http://dx.doi.org/10.1186/s13287-016-0344-x