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Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells

BACKGROUND: During the process of spermatogenesis, male germ cells undergo dramatic chromatin reorganization, whereby most histones are replaced by protamines, as part of the pathway to compact the genome into the small nuclear volume of the sperm head. Remarkably, approximately 90 % (human) to 95 %...

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Detalles Bibliográficos
Autores principales: Luense, Lacey J., Wang, Xiaoshi, Schon, Samantha B., Weller, Angela H., Lin Shiao, Enrique, Bryant, Jessica M., Bartolomei, Marisa S., Coutifaris, Christos, Garcia, Benjamin A., Berger, Shelley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915177/
https://www.ncbi.nlm.nih.gov/pubmed/27330565
http://dx.doi.org/10.1186/s13072-016-0072-6