A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis

Faithful chromosome segregation depends on the precise timing of chromatid separation, which is enforced by checkpoint signals generated at kinetochores. Here, we provide evidence that the C-terminal domain (CTD) of DNA topoisomerase IIα (Topo II) provides a novel function at inner centromeres of ki...

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Detalles Bibliográficos
Autores principales: Edgerton, Heather, Johansson, Marnie, Keifenheim, Daniel, Mukherjee, Soumya, Chacón, Jeremy M., Bachant, Jeff, Gardner, Melissa K., Clarke, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915189/
https://www.ncbi.nlm.nih.gov/pubmed/27325791
http://dx.doi.org/10.1083/jcb.201511080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915189/
https://www.ncbi.nlm.nih.gov/pubmed/27325791
http://dx.doi.org/10.1083/jcb.201511080

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