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A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair

Lysosome exocytosis plays a major role in resealing plasma membrane (PM) disruptions. This process involves two sequential steps. First, lysosomes are recruited to the periphery of the cell and then fuse with the damaged PM. However, the trafficking molecular machinery involved in lysosome exocytosi...

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Detalles Bibliográficos
Autores principales: Encarnação, Marisa, Espada, Lília, Escrevente, Cristina, Mateus, Denisa, Ramalho, José, Michelet, Xavier, Santarino, Inês, Hsu, Victor W., Brenner, Michael B., Barral, Duarte C., Vieira, Otília V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915190/
https://www.ncbi.nlm.nih.gov/pubmed/27325790
http://dx.doi.org/10.1083/jcb.201511093