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A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair
Lysosome exocytosis plays a major role in resealing plasma membrane (PM) disruptions. This process involves two sequential steps. First, lysosomes are recruited to the periphery of the cell and then fuse with the damaged PM. However, the trafficking molecular machinery involved in lysosome exocytosi...
Autores principales: | Encarnação, Marisa, Espada, Lília, Escrevente, Cristina, Mateus, Denisa, Ramalho, José, Michelet, Xavier, Santarino, Inês, Hsu, Victor W., Brenner, Michael B., Barral, Duarte C., Vieira, Otília V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915190/ https://www.ncbi.nlm.nih.gov/pubmed/27325790 http://dx.doi.org/10.1083/jcb.201511093 |
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