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The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915194/ https://www.ncbi.nlm.nih.gov/pubmed/27325789 http://dx.doi.org/10.1083/jcb.201602089 |