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The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Over the past decade, numerous advances have been made in the role and regulation of inflammasomes during pathogenic and sterile insults. An inflammasome complex comprises a sensor, an adaptor, and a zymogen procaspase-1. The functional output of inflammasome activation includes secretion of cytokin...

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Detalles Bibliográficos
Autores principales: Sharma, Deepika, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915194/
https://www.ncbi.nlm.nih.gov/pubmed/27325789
http://dx.doi.org/10.1083/jcb.201602089