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Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage

The GTPase RhoA promotes contractile ring assembly and furrow ingression during cytokinesis. Although many factors that regulate RhoA during cytokinesis have been characterized, the spatiotemporal regulatory logic remains undefined. We have developed an optogenetic probe to gain tight spatial and te...

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Detalles Bibliográficos
Autores principales: Wagner, Elizabeth, Glotzer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915195/
https://www.ncbi.nlm.nih.gov/pubmed/27298323
http://dx.doi.org/10.1083/jcb.201603025