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Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage
The GTPase RhoA promotes contractile ring assembly and furrow ingression during cytokinesis. Although many factors that regulate RhoA during cytokinesis have been characterized, the spatiotemporal regulatory logic remains undefined. We have developed an optogenetic probe to gain tight spatial and te...
Autores principales: | Wagner, Elizabeth, Glotzer, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915195/ https://www.ncbi.nlm.nih.gov/pubmed/27298323 http://dx.doi.org/10.1083/jcb.201603025 |
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