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Kaiso represses the expression of glucocorticoid receptor via a methylation-dependent mechanism and attenuates the anti-apoptotic activity of glucocorticoids in breast cancer cells

Kaiso is a Pox Virus and Zinc Finger (POZ-ZF) transcription factor with bi-modal DNA-binding specificity. Here, we demonstrated that Kaiso expression is inversely correlated with glucocorticoid receptor (GR) expression in breast carcinomas. Knockdown of Kaiso increased GR expression, while overexpre...

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Detalles Bibliográficos
Autores principales: Zhou, Lin, Zhong, Yan, Yang, Fang-hui, Li, Zi-bo, Zhou, Jiang, Liu, Xie-hong, Li, Min, Hu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915231/
https://www.ncbi.nlm.nih.gov/pubmed/26424557
http://dx.doi.org/10.5483/BMBRep.2016.49.3.151