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miR-185 inhibits endoplasmic reticulum stress-induced apoptosis by targeting Na(+)/H(+) exchanger-1 in the heart

Prolonged ER stress (ERS) can be associated with the induction of apoptotic cell death in various heart diseases. In this study, we searched for microRNAs affecting ERS in the heart using in silico and in vitro methods. We found that miR-185 directly targets the 3′-untranslated region of Na(+)/H(+)...

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Detalles Bibliográficos
Autores principales: Kim, Jin Ock, Kwon, Eun Jeong, Song, Dong Woo, Lee, Jong Sub, Kim, Do Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915239/
https://www.ncbi.nlm.nih.gov/pubmed/26521941
http://dx.doi.org/10.5483/BMBRep.2016.49.4.193