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miR-185 inhibits endoplasmic reticulum stress-induced apoptosis by targeting Na(+)/H(+) exchanger-1 in the heart
Prolonged ER stress (ERS) can be associated with the induction of apoptotic cell death in various heart diseases. In this study, we searched for microRNAs affecting ERS in the heart using in silico and in vitro methods. We found that miR-185 directly targets the 3′-untranslated region of Na(+)/H(+)...
Autores principales: | Kim, Jin Ock, Kwon, Eun Jeong, Song, Dong Woo, Lee, Jong Sub, Kim, Do Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915239/ https://www.ncbi.nlm.nih.gov/pubmed/26521941 http://dx.doi.org/10.5483/BMBRep.2016.49.4.193 |
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