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SETDB1 mediated FosB expression increases the cell proliferation rate during anticancer drug therapy

The efficacy of anticancer drugs depends on a variety of signaling pathways, which can be positively or negatively regulated. In this study, we show that SETDB1 HMTase is down-regulated at the transcriptional level by several anticancer drugs, due to its inherent instability. Using RNA sequence anal...

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Detalles Bibliográficos
Autores principales: Na, Han-Heom, Noh, Hee-Jung, Cheong, Hyang-Min, Kang, Yoonsung, Kim, Keun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915244/
https://www.ncbi.nlm.nih.gov/pubmed/26949019
http://dx.doi.org/10.5483/BMBRep.2016.49.4.031