Thioredoxin-Interacting Protein (TXNIP) Suppresses Expression of Glutamine Synthetase by Inducing Oxidative Stress in Retinal Muller Glia Under Diabetic Conditions

BACKGROUND: Diabetic retinopathy (DR) is a progressive neurodegenerative disease with early-stage symptoms such as dysfunction of Muller cells, which leads to ganglion cell death. Its pathogenesis is probably associated with oxidative stress and a recently discovered protein, thioredoxin-interacting...

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Detalles Bibliográficos
Autores principales: Zhou, Jia, Shen, Xi, Lu, Qiong, Zhang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915319/
https://www.ncbi.nlm.nih.gov/pubmed/27131835
http://dx.doi.org/10.12659/MSM.895916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915319/
https://www.ncbi.nlm.nih.gov/pubmed/27131835
http://dx.doi.org/10.12659/MSM.895916

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