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Impaired burrowing is the most prominent behavioral deficit of aging htau mice
htau mice are deficient of murine tau but express all six human tau isoforms, leading to gradual tau misprocessing and aggregation in brain areas relevant to Alzheimer’s disease. While histopathological changes in htau mice have been researched in the past, we focused here on functional consequences...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915442/ https://www.ncbi.nlm.nih.gov/pubmed/27167086 http://dx.doi.org/10.1016/j.neuroscience.2016.05.004 |