The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1

We recently demonstrated that WRAP53β acts as a key regulator of ubiquitin-dependent repair of DNA double-strand breaks. Here, we applied the proximity ligation assay (PLA) to show that at such breaks WRAP53β accumulates in close proximity to γH2AX and, furthermore as demonstrated by their co-immuno...

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Detalles Bibliográficos
Autores principales: Rassoolzadeh, Hanif, Coucoravas, Christos, Farnebo, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915514/
https://www.ncbi.nlm.nih.gov/pubmed/26734725
http://dx.doi.org/10.1080/19491034.2015.1106675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915514/
https://www.ncbi.nlm.nih.gov/pubmed/26734725
http://dx.doi.org/10.1080/19491034.2015.1106675

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