Transcriptional profiling of the mouse hippocampus supports an NMDAR‐mediated neurotoxic mode of action for benzo[a]pyrene

Benzo[a]pyrene (BaP) is a genotoxic carcinogen and a neurotoxicant. The neurotoxicity of BaP is proposed to arise from either genotoxicity leading to neuronal cell death, or perturbed expression of N‐methyl‐d‐aspartate receptor (NMDAR) subunits. To explore these hypotheses, we profiled hippocampal g...

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Detalles Bibliográficos
Autores principales: Chepelev, Nikolai L., Long, Alexandra S., Bowers, Wayne J., Gagné, Rémi, Williams, Andrew, Kuo, Byron, Phillips, David H., Arlt, Volker M., White, Paul A., Yauk, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915531/
https://www.ncbi.nlm.nih.gov/pubmed/27195522
http://dx.doi.org/10.1002/em.22020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915531/
https://www.ncbi.nlm.nih.gov/pubmed/27195522
http://dx.doi.org/10.1002/em.22020

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