Differences in quantification of DNA double-strand breaks assessed by 53BP1/γH2AX focus formation assays and the comet assay in mammalian cells treated with irradiation and N-acetyl-L-cysteine

The biological effect of ionizing radiation (IR) on genomic DNA is thought to be either direct or indirect; the latter is mediated by IR induction of free radicals and reactive oxygen species (ROS). This study was designed to evaluate the effect of N-acetyl-L-cysteine (NAC), a well-known ROS-scaveng...

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Detalles Bibliográficos
Autores principales: Kurashige, Tomomi, Shimamura, Mika, Nagayama, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915540/
https://www.ncbi.nlm.nih.gov/pubmed/26951077
http://dx.doi.org/10.1093/jrr/rrw001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915540/
https://www.ncbi.nlm.nih.gov/pubmed/26951077
http://dx.doi.org/10.1093/jrr/rrw001

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