Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

Modest elevations in C-reactive protein (CRP) are associated with type 2 diabetes. We previously revealed in mice that increased CRP causes insulin resistance and mice globally deficient in the CRP receptor Fcγ receptor IIB (FcγRIIB) were protected from the disorder. FcγRIIB is expressed in numerous...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanigaki, Keiji, Chambliss, Ken L., Yuhanna, Ivan S., Sacharidou, Anastasia, Ahmed, Mohamed, Atochin, Dmitriy N., Huang, Paul L., Shaul, Philip W., Mineo, Chieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915578/
https://www.ncbi.nlm.nih.gov/pubmed/27207525
http://dx.doi.org/10.2337/db15-1605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915578/
https://www.ncbi.nlm.nih.gov/pubmed/27207525
http://dx.doi.org/10.2337/db15-1605

Ejemplares similares