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KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection

Following envelope mediated fusion, the HIV-1 core is released into the cytoplasm of the target cell and undergoes a series of trafficking and replicative steps that result in the nuclear import of the viral genome, which ultimately leads to the integration of the proviral DNA into the host cell gen...

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Detalles Bibliográficos
Autores principales: Dharan, Adarsh, Talley, Sarah, Tripathi, Abhishek, Mamede, João I., Majetschak, Matthias, Hope, Thomas J., Campbell, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915687/
https://www.ncbi.nlm.nih.gov/pubmed/27327622
http://dx.doi.org/10.1371/journal.ppat.1005700