Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity

In order for a virus to persist, there must be a balance between viral replication and immune clearance. It is commonly believed that adaptive immunity drives clearance of viral infections and, thus, dysfunction or viral evasion of adaptive immunity is required for a virus to persist. Type I interfe...

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Detalles Bibliográficos
Autores principales: Nice, Timothy J., Osborne, Lisa C., Tomov, Vesselin T., Artis, David, Wherry, E. John, Virgin, Herbert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915689/
https://www.ncbi.nlm.nih.gov/pubmed/27327515
http://dx.doi.org/10.1371/journal.ppat.1005684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915689/
https://www.ncbi.nlm.nih.gov/pubmed/27327515
http://dx.doi.org/10.1371/journal.ppat.1005684

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