Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

Cardiac electrophysiology models have been developed for over 50 years, and now include detailed descriptions of individual ion currents and sub-cellular calcium handling. It is commonly accepted that there are many uncertainties in these systems, with quantities such as ion channel kinetics or expr...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnstone, Ross H., Chang, Eugene T.Y., Bardenet, Rémi, de Boer, Teun P., Gavaghan, David J., Pathmanathan, Pras, Clayton, Richard H., Mirams, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915860/
https://www.ncbi.nlm.nih.gov/pubmed/26611884
http://dx.doi.org/10.1016/j.yjmcc.2015.11.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915860/
https://www.ncbi.nlm.nih.gov/pubmed/26611884
http://dx.doi.org/10.1016/j.yjmcc.2015.11.018

Ejemplares similares