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Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
Cardiac electrophysiology models have been developed for over 50 years, and now include detailed descriptions of individual ion currents and sub-cellular calcium handling. It is commonly accepted that there are many uncertainties in these systems, with quantities such as ion channel kinetics or expr...
Autores principales: | Johnstone, Ross H., Chang, Eugene T.Y., Bardenet, Rémi, de Boer, Teun P., Gavaghan, David J., Pathmanathan, Pras, Clayton, Richard H., Mirams, Gary R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915860/ https://www.ncbi.nlm.nih.gov/pubmed/26611884 http://dx.doi.org/10.1016/j.yjmcc.2015.11.018 |
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