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Id2 reinforces T(H)1 cell differentiation and inhibits E2A to repress T(FH) cell differentiation

Differentiation of T helper (T(H)) effector subsets is critical for host protection. E protein transcription factors and Id proteins are important arbiters of T cell development, but their role in differentiation of T(H)1 and T(FH) cells is not well understood. T(H)1 cells showed robust Id2 expressi...

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Detalles Bibliográficos
Autores principales: Shaw, Laura A., Bélanger, Simon, Omilusik, Kyla D., Cho, Sunglim, Scott-Browne, James P., Nance, J. Philip, Goulding, John, Lasorella, Anna, Lu, Li-Fan, Crotty, Shane, Goldrath, Ananda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915968/
https://www.ncbi.nlm.nih.gov/pubmed/27213691
http://dx.doi.org/10.1038/ni.3461