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Id2 reinforces T(H)1 cell differentiation and inhibits E2A to repress T(FH) cell differentiation
Differentiation of T helper (T(H)) effector subsets is critical for host protection. E protein transcription factors and Id proteins are important arbiters of T cell development, but their role in differentiation of T(H)1 and T(FH) cells is not well understood. T(H)1 cells showed robust Id2 expressi...
Autores principales: | Shaw, Laura A., Bélanger, Simon, Omilusik, Kyla D., Cho, Sunglim, Scott-Browne, James P., Nance, J. Philip, Goulding, John, Lasorella, Anna, Lu, Li-Fan, Crotty, Shane, Goldrath, Ananda W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915968/ https://www.ncbi.nlm.nih.gov/pubmed/27213691 http://dx.doi.org/10.1038/ni.3461 |
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