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Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins

BACKGROUND: There are some reports about the antitumor effects of statins in these days. Statins decrease the level of cholesterol in the blood by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Inhibition of this enzyme decreases intracellular cholesterol synthesis. Thus, the expression...

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Detalles Bibliográficos
Autores principales: Furuya, Yosuke, Sekine, Yoshitaka, Kato, Haruo, Miyazawa, Yoshiyuki, Koike, Hidekazu, Suzuki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Pacific Prostate Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916060/
https://www.ncbi.nlm.nih.gov/pubmed/27358845
http://dx.doi.org/10.1016/j.prnil.2016.02.003