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Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins
BACKGROUND: There are some reports about the antitumor effects of statins in these days. Statins decrease the level of cholesterol in the blood by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Inhibition of this enzyme decreases intracellular cholesterol synthesis. Thus, the expression...
Autores principales: | Furuya, Yosuke, Sekine, Yoshitaka, Kato, Haruo, Miyazawa, Yoshiyuki, Koike, Hidekazu, Suzuki, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asian Pacific Prostate Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916060/ https://www.ncbi.nlm.nih.gov/pubmed/27358845 http://dx.doi.org/10.1016/j.prnil.2016.02.003 |
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