Characterization of pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia with kinase fusions in Japan

Recent studies revealed that a substantial proportion of patients with high-risk B-cell precursor acute lymphoblastic leukemia (BCP-ALL) harbor fusions involving tyrosine kinase and cytokine receptors, such as ABL1, PDGFRB, JAK2 and CRLF2, which are targeted by tyrosine kinase inhibitors (TKIs). In...

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Detalles Bibliográficos
Autores principales: Imamura, T, Kiyokawa, N, Kato, M, Imai, C, Okamoto, Y, Yano, M, Ohki, K, Yamashita, Y, Kodama, Y, Saito, A, Mori, M, Ishimaru, S, Deguchi, T, Hashii, Y, Shimomura, Y, Hori, T, Kato, K, Goto, H, Ogawa, C, Koh, K, Taki, T, Manabe, A, Sato, A, Kikuta, A, Adachi, S, Horibe, K, Ohara, A, Watanabe, A, Kawano, Y, Ishii, E, Shimada, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916297/
https://www.ncbi.nlm.nih.gov/pubmed/27176795
http://dx.doi.org/10.1038/bcj.2016.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916297/
https://www.ncbi.nlm.nih.gov/pubmed/27176795
http://dx.doi.org/10.1038/bcj.2016.28

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