Cargando…

Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation

The exact regulatory mechanisms of carboxyl-terminal modulator protein (CTMP) and its downstream pathways in cancer have been controversial and are not completely understood. Here, we report a new mechanism of regulation of Akt serine/threonine kinase, one of the most important dysregulated signals...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Jae Won, Jung, Seung-Nam, Kim, Ju-Hee, Shim, Geun-Ae, Park, Hee Sung, Liu, Lihua, Kim, Jin Man, Park, Jongsun, Koo, Bon Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916413/
https://www.ncbi.nlm.nih.gov/pubmed/27328758
http://dx.doi.org/10.1038/srep28503