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Carboxyl-Terminal Modulator Protein Positively Acts as an Oncogenic Driver in Head and Neck Squamous Cell Carcinoma via Regulating Akt phosphorylation
The exact regulatory mechanisms of carboxyl-terminal modulator protein (CTMP) and its downstream pathways in cancer have been controversial and are not completely understood. Here, we report a new mechanism of regulation of Akt serine/threonine kinase, one of the most important dysregulated signals...
Autores principales: | Chang, Jae Won, Jung, Seung-Nam, Kim, Ju-Hee, Shim, Geun-Ae, Park, Hee Sung, Liu, Lihua, Kim, Jin Man, Park, Jongsun, Koo, Bon Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916413/ https://www.ncbi.nlm.nih.gov/pubmed/27328758 http://dx.doi.org/10.1038/srep28503 |
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