The impact of genotype calling errors on family-based studies

Family-based sequencing studies have unique advantages in enriching rare variants, controlling population stratification, and improving genotype calling. Standard genotype calling algorithms are less likely to call rare variants correctly, often mistakenly calling heterozygotes as reference homozygo...

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Detalles Bibliográficos
Autores principales: Yan, Qi, Chen, Rui, Sutcliffe, James S., Cook, Edwin H., Weeks, Daniel E., Li, Bingshan, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916415/
https://www.ncbi.nlm.nih.gov/pubmed/27328765
http://dx.doi.org/10.1038/srep28323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916415/
https://www.ncbi.nlm.nih.gov/pubmed/27328765
http://dx.doi.org/10.1038/srep28323

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