Cargando…

Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis

Lymphocyte chemotaxis plays important roles in immunological reactions, although the mechanism of its regulation is still unclear. We found that the cytosolic Na(+)-dependent mitochondrial Ca(2+) efflux transporter, NCLX, regulates B lymphocyte chemotaxis. Inhibiting or silencing NCLX in A20 and DT4...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Bongju, Takeuchi, Ayako, Hikida, Masaki, Matsuoka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916421/
https://www.ncbi.nlm.nih.gov/pubmed/27328625
http://dx.doi.org/10.1038/srep28378