Intrinsic hepatocyte dedifferentiation is accompanied by upregulation of mesenchymal markers, protein sialylation and core alpha 1,6 linked fucosylation

Alterations in N-linked glycosylation have long been associated with cancer but for the most part, the reasons why have remained poorly understood. Here we show that increased core fucosylation is associated with de-differentiation of primary hepatocytes and with the appearance of markers indicative...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehta, Anand, Comunale, Mary Ann, Rawat, Siddhartha, Casciano, Jessica C., Lamontagne, Jason, Herrera, Harmin, Ramanathan, Aarti, Betesh, Lucy, Wang, Mengjun, Norton, Pamela, Steel, Laura F., Bouchard, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916422/
https://www.ncbi.nlm.nih.gov/pubmed/27328854
http://dx.doi.org/10.1038/srep27965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916422/
https://www.ncbi.nlm.nih.gov/pubmed/27328854
http://dx.doi.org/10.1038/srep27965

Ejemplares similares