From non-covalent binding to irreversible DNA lesions: nile blue and nile red as photosensitizing agents

We report a molecular modeling study, coupled with spectroscopy experiments, on the behavior of two well known organic dyes, nile blue and nile red, when interacting with B-DNA. In particular, we evidence the presence of two competitive binding modes, for both drugs. However their subsequent photoph...

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Detalles Bibliográficos
Autores principales: Gattuso, Hugo, Besancenot, Vanessa, Grandemange, Stéphanie, Marazzi, Marco, Monari, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916457/
https://www.ncbi.nlm.nih.gov/pubmed/27329409
http://dx.doi.org/10.1038/srep28480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916457/
https://www.ncbi.nlm.nih.gov/pubmed/27329409
http://dx.doi.org/10.1038/srep28480

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