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From non-covalent binding to irreversible DNA lesions: nile blue and nile red as photosensitizing agents
We report a molecular modeling study, coupled with spectroscopy experiments, on the behavior of two well known organic dyes, nile blue and nile red, when interacting with B-DNA. In particular, we evidence the presence of two competitive binding modes, for both drugs. However their subsequent photoph...
Autores principales: | Gattuso, Hugo, Besancenot, Vanessa, Grandemange, Stéphanie, Marazzi, Marco, Monari, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916457/ https://www.ncbi.nlm.nih.gov/pubmed/27329409 http://dx.doi.org/10.1038/srep28480 |
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